Результаты исследований: Вклад в журнал › Статья › Рецензирование
Результаты исследований: Вклад в журнал › Статья › Рецензирование
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TY - JOUR
T1 - Two-step synthesis of indeno[1,2-b]furazanopyrazines through combination of the SNH and Heck reactions
AU - Kvashnin, Yuriy a.
AU - Belyaev, Danila v.
AU - Kodess, Mikhail i.
AU - Ezhikova, Marina a.
AU - Rusinov, Gennady l.
AU - Verbitskiy, Egor v.
AU - Charushin, Valery n.
PY - 2023/11/1
Y1 - 2023/11/1
N2 - Enamines generated in situ from aliphatic amines and acetone react with 5-(2-bromophenyl)furazano[3,4-b]pyrazines via the nucleophilic substitution of hydrogen atom of the pyrazine ring. A representative of 9H-indeno[1,2-b]furazanopyrazin-9-ylidene ring system has been accessed by exploiting the intramolecular Heck cyclization of the obtained SNH-product. Several compounds derived from furazano[3,4-b]pyrazin-5-yl]prop-1-en-2-amines, proved to exhibit a bacteriostatic activity in vitro against Mycobacterium tuberculosis H37Rv.
AB - Enamines generated in situ from aliphatic amines and acetone react with 5-(2-bromophenyl)furazano[3,4-b]pyrazines via the nucleophilic substitution of hydrogen atom of the pyrazine ring. A representative of 9H-indeno[1,2-b]furazanopyrazin-9-ylidene ring system has been accessed by exploiting the intramolecular Heck cyclization of the obtained SNH-product. Several compounds derived from furazano[3,4-b]pyrazin-5-yl]prop-1-en-2-amines, proved to exhibit a bacteriostatic activity in vitro against Mycobacterium tuberculosis H37Rv.
UR - https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=tsmetrics&SrcApp=tsm_test&DestApp=WOS_CPL&DestLinkType=FullRecord&KeyUT=001128136700001
UR - http://www.scopus.com/inward/record.url?partnerID=8YFLogxK&scp=85183717530
U2 - 10.1016/j.mencom.2023.10.004
DO - 10.1016/j.mencom.2023.10.004
M3 - Article
VL - 33
SP - 753
EP - 755
JO - Mendeleev Communications
JF - Mendeleev Communications
SN - 0959-9436
IS - 6
ER -
ID: 50707657