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Synthesis and cytotoxic activity of (2-arylquinazolin-4-yl)hydrazones of 2-hydroxybenzaldehydes. / Nosova, Emiliya v.; Butorin, Ilya i.; Likhacheva, Margarita d. et al.
In: Chimica Techno Acta, Vol. 10, No. 2, 202310211, 2023.

Research output: Contribution to journal › Article › peer-review

Harvard

Nosova, EV, Butorin, II, Likhacheva, MD & Kotovskaya, SK 2023, 'Synthesis and cytotoxic activity of (2-arylquinazolin-4-yl)hydrazones of 2-hydroxybenzaldehydes', Chimica Techno Acta, vol. 10, no. 2, 202310211. https://doi.org/10.15826/chimtech.2023.10.2.11

APA

Nosova, E. V., Butorin, I. I., Likhacheva, M. D., & Kotovskaya, S. K. (2023). Synthesis and cytotoxic activity of (2-arylquinazolin-4-yl)hydrazones of 2-hydroxybenzaldehydes. Chimica Techno Acta, 10(2), [202310211]. https://doi.org/10.15826/chimtech.2023.10.2.11

Vancouver

Nosova EV, Butorin II, Likhacheva MD, Kotovskaya SK. Synthesis and cytotoxic activity of (2-arylquinazolin-4-yl)hydrazones of 2-hydroxybenzaldehydes. Chimica Techno Acta. 2023;10(2):202310211. doi: 10.15826/chimtech.2023.10.2.11

Author

Nosova, Emiliya v. ; Butorin, Ilya i. ; Likhacheva, Margarita d. et al. / Synthesis and cytotoxic activity of (2-arylquinazolin-4-yl)hydrazones of 2-hydroxybenzaldehydes. In: Chimica Techno Acta. 2023 ; Vol. 10, No. 2.

BibTeX

@article{7bf6a85fd9bf46678e4de79f7685d35a,
title = "Synthesis and cytotoxic activity of (2-arylquinazolin-4-yl)hydrazones of 2-hydroxybenzaldehydes",
abstract = "2-Phenyl-6,7-difluoro and 2-(4-fluorophenyl)quinazoline derivatives bearing salicylidenhydrazino fragments at position 4 were prepared based on 4,5-difluoroantranilic acid or anthranilamide. Molecular docking to casein kinase 2 was performed; compounds with high in silico activity to CK2 were revealed. Cytotoxic activity of the synthesized compounds was studied on cancer cell line MDA-MB-231 and normal cell line WI26 VA4.",
author = "Nosova, {Emiliya v.} and Butorin, {Ilya i.} and Likhacheva, {Margarita d.} and Kotovskaya, {Svetlana k.}",
note = "This work was supported by the Ministry of Science and Higher Education of the Russian Federation, State Contract no FEUZ-2023-0021 (N687.42B.325/23).",
year = "2023",
doi = "10.15826/chimtech.2023.10.2.11",
language = "English",
volume = "10",
journal = "Chimica Techno Acta",
issn = "2409-5613",
publisher = "Издательство Уральского университета",
number = "2",

}

RIS

TY - JOUR

T1 - Synthesis and cytotoxic activity of (2-arylquinazolin-4-yl)hydrazones of 2-hydroxybenzaldehydes

AU - Nosova, Emiliya v.

AU - Butorin, Ilya i.

AU - Likhacheva, Margarita d.

AU - Kotovskaya, Svetlana k.

N1 - This work was supported by the Ministry of Science and Higher Education of the Russian Federation, State Contract no FEUZ-2023-0021 (N687.42B.325/23).

PY - 2023

Y1 - 2023

N2 - 2-Phenyl-6,7-difluoro and 2-(4-fluorophenyl)quinazoline derivatives bearing salicylidenhydrazino fragments at position 4 were prepared based on 4,5-difluoroantranilic acid or anthranilamide. Molecular docking to casein kinase 2 was performed; compounds with high in silico activity to CK2 were revealed. Cytotoxic activity of the synthesized compounds was studied on cancer cell line MDA-MB-231 and normal cell line WI26 VA4.

AB - 2-Phenyl-6,7-difluoro and 2-(4-fluorophenyl)quinazoline derivatives bearing salicylidenhydrazino fragments at position 4 were prepared based on 4,5-difluoroantranilic acid or anthranilamide. Molecular docking to casein kinase 2 was performed; compounds with high in silico activity to CK2 were revealed. Cytotoxic activity of the synthesized compounds was studied on cancer cell line MDA-MB-231 and normal cell line WI26 VA4.

UR - http://www.scopus.com/inward/record.url?partnerID=8YFLogxK&scp=85162133089

UR - https://elibrary.ru/item.asp?id=54268153

U2 - 10.15826/chimtech.2023.10.2.11

DO - 10.15826/chimtech.2023.10.2.11

M3 - Article

VL - 10

JO - Chimica Techno Acta

JF - Chimica Techno Acta

SN - 2409-5613

IS - 2

M1 - 202310211

ER -

ID: 41588035