Fats and low molecular weight alcohols in the transesterification reaction are heterogeneous immiscible liquids separated from each other by a mobile phase boundary. The features of mass transfer across the phase boundary when producing biodiesel fuel in the "liquid-liquid" system were considered. Information research methods: analytical, statistical, comparative and information-logical methods of processing and analysis of initial information, methods of a systematic approach, were used in the study of factors that determine the effectiveness of the use of motor fuels in crop production. A variant of the mechanism of mass transfer across the interface is proposed. As a first approximation, it was assumed that in order to intensify the transesterification process, it is necessary to create conditions for improving the solubility of the components of the fat-alcohol system along with a change in the area of their interaction by creating a high degree of turbulence in this system. It was found that for these purposes it is advisable to use acoustic vibrations. It was revealed that in the degree of intensification of processes, acoustic methods are several times superior to electromagnetic ones. It has been proven that the kinetics of the process at the beginning of the reaction is controlled by the mass transfer of reagents by diffusion. The kinetics of the process begins to be controlled by the chemical reaction when esters of higher aliphatic acids and monohydric alcohols appear in the reaction mass, which are soluble both in vegetable oil and in alcohol. It is noted that an accurate calculation of the mass transfer process is complicated by the existence of surfactants and various inclusions in the "fat-alcohol" system. It was found that the resulting esters of the corresponding fatty acids, on the one hand, play the role of co-solvents of the system, contributing to the intensification of the process, and on the other hand, they act as surfactants that inhibit mass transfer.