Результаты исследований: Вклад в журнал › Обзорная статья › Рецензирование
Результаты исследований: Вклад в журнал › Обзорная статья › Рецензирование
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TY - JOUR
T1 - Recent Advances in the Synthesis of Quinoxalines. A Mini Review
AU - Avula, Balakrishna
AU - Reddivari, Chenna
AU - Muchumarri, Rama Mohan Reddy
AU - Eraganaboyina, Suneetha
AU - Zyryanov, Grigory
AU - Nemallapudi, Bakthavatchala
PY - 2024/1/2
Y1 - 2024/1/2
N2 - Quinoxalines are an important group of N-heterocyclic compounds, which are present in a variety of natural and synthetic compounds possessing physicochemical properties and pharmacological activities. Since the earliest studies, their unique properties have led the chemical community, to embrace the challenge of synthesizing new Quinoxalines. This bioactive moiety can act as a versatile building block intermediate in synthesizing novel heterocyclic scaffolds and is considered as prime focus in medicinal chemistry research. This review aims to highlight the recent synthetic strategies and various routes employed to design and synthesize quinoxalines. Initially, we have discussed the classical methods of synthesis followed by modern methods and green methods, with an overview pertaining to their structure-activity-relationship (SAR). We entrust that, this mini review will offer a broad perspective and insights among the readers in the development of new quinoxalines scaffolds with rich bio-potent applications.
AB - Quinoxalines are an important group of N-heterocyclic compounds, which are present in a variety of natural and synthetic compounds possessing physicochemical properties and pharmacological activities. Since the earliest studies, their unique properties have led the chemical community, to embrace the challenge of synthesizing new Quinoxalines. This bioactive moiety can act as a versatile building block intermediate in synthesizing novel heterocyclic scaffolds and is considered as prime focus in medicinal chemistry research. This review aims to highlight the recent synthetic strategies and various routes employed to design and synthesize quinoxalines. Initially, we have discussed the classical methods of synthesis followed by modern methods and green methods, with an overview pertaining to their structure-activity-relationship (SAR). We entrust that, this mini review will offer a broad perspective and insights among the readers in the development of new quinoxalines scaffolds with rich bio-potent applications.
UR - http://www.scopus.com/inward/record.url?partnerID=8YFLogxK&scp=85146446471
UR - https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=tsmetrics&SrcApp=tsm_test&DestApp=WOS_CPL&DestLinkType=FullRecord&KeyUT=000914740300001
U2 - 10.1080/10406638.2023.2167215
DO - 10.1080/10406638.2023.2167215
M3 - Review article
VL - 44
SP - 634
EP - 670
JO - Polycyclic Aromatic Compounds
JF - Polycyclic Aromatic Compounds
SN - 1040-6638
IS - 1
ER -
ID: 50640083