Результаты исследований: Вклад в журнал › Статья › Рецензирование
Результаты исследований: Вклад в журнал › Статья › Рецензирование
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TY - JOUR
T1 - Reaction of 1,2,4-Triazine-5-carbonitriles with 5-[(2-Hydroxyethyl)sulfanyl]- and 5-{[2-(2-Hydroxyethoxy)-ethyl]sulfanyl}-3-amino-1,2,4-triazoles1
AU - Krinochkin, A. P.
AU - Ladin, E. D.
AU - Shtaitz, Ya. K.
AU - Kudryashova, E. A.
AU - Kopchuk, D. S.
AU - Gorbunov, E. B.
AU - Shafran, Yu. M.
AU - Zyryanov, G. V.
AU - Rusinov, V. L.
N1 - The work was financially supported by the Russian Science Foundation (project no. 20-13-00142-P, https://rscf.ru/project/20-13-00142/, synthesis of the final products) and Grant Council under the President of the Russian Federation (grant no. MD-167.2021.1.3, synthesis of the starting aminotriazoles).
PY - 2023/11/1
Y1 - 2023/11/1
N2 - The solvent-free reaction of 1,2,4-triazine-5-carbonitriles with newly synthesized 5-[(2-hydroxyethyl)sulfanyl]- and 5-{[2-(2-hydroxyethoxy)ethyl]sulfanyl}-3-amino-1,2,4-triazoles under heating was studied. It was shown that in the case when the C5 atom of the 1,2,4-triazole ring bears hydroxy(ethoxy)ethylsulfanyl substituents, 5-amino-1,2,4-triazines are formed as the main reaction products, while the ipso-substitution products of the C5-cyano group of the substituted 1,2,4-triazole ring were isolated only as by-products. With a 1,2,4-triazole with a monoethylene glycol fragment at the C5 position, a complex mixture of products was formed.
AB - The solvent-free reaction of 1,2,4-triazine-5-carbonitriles with newly synthesized 5-[(2-hydroxyethyl)sulfanyl]- and 5-{[2-(2-hydroxyethoxy)ethyl]sulfanyl}-3-amino-1,2,4-triazoles under heating was studied. It was shown that in the case when the C5 atom of the 1,2,4-triazole ring bears hydroxy(ethoxy)ethylsulfanyl substituents, 5-amino-1,2,4-triazines are formed as the main reaction products, while the ipso-substitution products of the C5-cyano group of the substituted 1,2,4-triazole ring were isolated only as by-products. With a 1,2,4-triazole with a monoethylene glycol fragment at the C5 position, a complex mixture of products was formed.
UR - http://www.scopus.com/inward/record.url?partnerID=8YFLogxK&scp=85184440194
UR - https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=tsmetrics&SrcApp=tsm_test&DestApp=WOS_CPL&DestLinkType=FullRecord&KeyUT=001157742100020
U2 - 10.1134/S1070428023110210
DO - 10.1134/S1070428023110210
M3 - Article
VL - 59
SP - 1998
EP - 2002
JO - Russian Journal of Organic Chemistry
JF - Russian Journal of Organic Chemistry
SN - 1070-4280
IS - 11
ER -
ID: 52961029