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Antioxidant properties of 2,5-substituted 6H-1,3,4-thiadiazines promising for experimental therapy of diabetes mellitus. / Gerasimova, E. L.; Gazizullina, E. G.; Igdisanova, D. I. и др.
в: Russian Chemical Bulletin, Том 71, № 12, 01.12.2022, стр. 2730-2739.

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@article{3686432ab84b4b7d88e136fff3b4fe40,
title = "Antioxidant properties of 2,5-substituted 6H-1,3,4-thiadiazines promising for experimental therapy of diabetes mellitus",
abstract = "Antioxidant properties of synthetic 2,5-substituted 6H-1,3,4-thiadiazines were comprehensively studied using potentiometric methods based on the reactions of electron transfer (ET mechanism) and hydrogen atom transfer (HAT mechanism) from the anti-oxidant to oxidant molecule. The kinetic parameters of the reactions with various oxidizing agents were estimated taking into account peculiarities of the transformation of 2,5-substituted 6H-1,3,4-thiadiazines in solution. The relationships “structure—antioxidant properties” are established. The role of the electron-donating and electron-withdrawing properties of substituents in positions 2 and 5 of the 1,3,4-thiadiazine ring in the manifestation of antioxidant properties is examined. ",
author = "Gerasimova, {E. L.} and Gazizullina, {E. G.} and Igdisanova, {D. I.} and Sidorova, {L. P.} and Tseitler, {T. A.} and Emelianov, {V. V.} and Chupakhin, {O. N.} and Ivanova, {A. V.}",
note = "This work was financially supported by the Russian Foundation for Basic Research (Project No. 19-29-08015 mk).",
year = "2022",
month = dec,
day = "1",
doi = "10.1007/s11172-022-3702-0",
language = "English",
volume = "71",
pages = "2730--2739",
journal = "Russian Chemical Bulletin",
issn = "1066-5285",
publisher = "Springer",
number = "12",

}

RIS

TY - JOUR

T1 - Antioxidant properties of 2,5-substituted 6H-1,3,4-thiadiazines promising for experimental therapy of diabetes mellitus

AU - Gerasimova, E. L.

AU - Gazizullina, E. G.

AU - Igdisanova, D. I.

AU - Sidorova, L. P.

AU - Tseitler, T. A.

AU - Emelianov, V. V.

AU - Chupakhin, O. N.

AU - Ivanova, A. V.

N1 - This work was financially supported by the Russian Foundation for Basic Research (Project No. 19-29-08015 mk).

PY - 2022/12/1

Y1 - 2022/12/1

N2 - Antioxidant properties of synthetic 2,5-substituted 6H-1,3,4-thiadiazines were comprehensively studied using potentiometric methods based on the reactions of electron transfer (ET mechanism) and hydrogen atom transfer (HAT mechanism) from the anti-oxidant to oxidant molecule. The kinetic parameters of the reactions with various oxidizing agents were estimated taking into account peculiarities of the transformation of 2,5-substituted 6H-1,3,4-thiadiazines in solution. The relationships “structure—antioxidant properties” are established. The role of the electron-donating and electron-withdrawing properties of substituents in positions 2 and 5 of the 1,3,4-thiadiazine ring in the manifestation of antioxidant properties is examined.

AB - Antioxidant properties of synthetic 2,5-substituted 6H-1,3,4-thiadiazines were comprehensively studied using potentiometric methods based on the reactions of electron transfer (ET mechanism) and hydrogen atom transfer (HAT mechanism) from the anti-oxidant to oxidant molecule. The kinetic parameters of the reactions with various oxidizing agents were estimated taking into account peculiarities of the transformation of 2,5-substituted 6H-1,3,4-thiadiazines in solution. The relationships “structure—antioxidant properties” are established. The role of the electron-donating and electron-withdrawing properties of substituents in positions 2 and 5 of the 1,3,4-thiadiazine ring in the manifestation of antioxidant properties is examined.

UR - http://www.scopus.com/inward/record.url?partnerID=8YFLogxK&scp=85149073349

UR - https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=tsmetrics&SrcApp=tsm_test&DestApp=WOS_CPL&DestLinkType=FullRecord&KeyUT=000971659000017

U2 - 10.1007/s11172-022-3702-0

DO - 10.1007/s11172-022-3702-0

M3 - Article

VL - 71

SP - 2730

EP - 2739

JO - Russian Chemical Bulletin

JF - Russian Chemical Bulletin

SN - 1066-5285

IS - 12

ER -

ID: 35502479