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2-(4-Oxo-1,3-thiazolidin-2-ylidene)acetamid as promising scaffold for designing new antifungal compounds. / Obydennov, Konstantin L.; Kalinina, Tatiana A.; Ryabova, Daria V. и др.
в: Chimica Techno Acta, Том 10, № 1, 2023.

Результаты исследований: Вклад в журнал › Статья › Рецензирование

Harvard

Obydennov, KL, Kalinina, TA, Ryabova, DV, Kosterina, MF & Glukhareva, TV 2023, '2-(4-Oxo-1,3-thiazolidin-2-ylidene)acetamid as promising scaffold for designing new antifungal compounds', Chimica Techno Acta, Том. 10, № 1. https://doi.org/10.15826/chimtech.2023.10.1.06

APA

Obydennov, K. L., Kalinina, T. A., Ryabova, D. V., Kosterina, M. F., & Glukhareva, T. V. (2023). 2-(4-Oxo-1,3-thiazolidin-2-ylidene)acetamid as promising scaffold for designing new antifungal compounds. Chimica Techno Acta, 10(1). https://doi.org/10.15826/chimtech.2023.10.1.06

Vancouver

Obydennov KL, Kalinina TA, Ryabova DV, Kosterina MF, Glukhareva TV. 2-(4-Oxo-1,3-thiazolidin-2-ylidene)acetamid as promising scaffold for designing new antifungal compounds. Chimica Techno Acta. 2023;10(1). doi: 10.15826/chimtech.2023.10.1.06

Author

Obydennov, Konstantin L. ; Kalinina, Tatiana A. ; Ryabova, Daria V. и др. / 2-(4-Oxo-1,3-thiazolidin-2-ylidene)acetamid as promising scaffold for designing new antifungal compounds. в: Chimica Techno Acta. 2023 ; Том 10, № 1.

BibTeX

@article{1c6d0f9aad3f4c0aacd1065b5f0ed203,
title = "2-(4-Oxo-1,3-thiazolidin-2-ylidene)acetamid as promising scaffold for designing new antifungal compounds",
abstract = "1,3-Thiazolidin-4-one derivatives with an exocyclic C=C double bond in position 2 of the hetero ring have a wide spectrum of biological activity, but their fungicidal activity has not been studied as much as it should be. This paper presents a simple and convenient approach for obtaining potential antifungal agents based on 2-(4-oxo-1,3-thiazolidin-2-ylidene)acetamides. The first examples of evaluating the fungicidal activity of 8 obtained compounds on 8 strains of phytopathogenic fungi are presented. A highly active compound 4e with EC50 of 0.85 and 2.29 µg/mL against A. solani and P. lingam, respectively, was found to be promising for further study.",
author = "Obydennov, {Konstantin L.} and Kalinina, {Tatiana A.} and Ryabova, {Daria V.} and Kosterina, {Maria F.} and Glukhareva, {Tatiana V.}",
note = "This research was supported by the Russian Science Foundation and Government of Sverdlovsk region, Joint Grant No 22-26-20124, https://rscf.ru/en/project/22-26-20124.",
year = "2023",
doi = "10.15826/chimtech.2023.10.1.06",
language = "English",
volume = "10",
journal = "Chimica Techno Acta",
issn = "2409-5613",
publisher = "Издательство Уральского университета",
number = "1",

}

RIS

TY - JOUR

T1 - 2-(4-Oxo-1,3-thiazolidin-2-ylidene)acetamid as promising scaffold for designing new antifungal compounds

AU - Obydennov, Konstantin L.

AU - Kalinina, Tatiana A.

AU - Ryabova, Daria V.

AU - Kosterina, Maria F.

AU - Glukhareva, Tatiana V.

N1 - This research was supported by the Russian Science Foundation and Government of Sverdlovsk region, Joint Grant No 22-26-20124, https://rscf.ru/en/project/22-26-20124.

PY - 2023

Y1 - 2023

N2 - 1,3-Thiazolidin-4-one derivatives with an exocyclic C=C double bond in position 2 of the hetero ring have a wide spectrum of biological activity, but their fungicidal activity has not been studied as much as it should be. This paper presents a simple and convenient approach for obtaining potential antifungal agents based on 2-(4-oxo-1,3-thiazolidin-2-ylidene)acetamides. The first examples of evaluating the fungicidal activity of 8 obtained compounds on 8 strains of phytopathogenic fungi are presented. A highly active compound 4e with EC50 of 0.85 and 2.29 µg/mL against A. solani and P. lingam, respectively, was found to be promising for further study.

AB - 1,3-Thiazolidin-4-one derivatives with an exocyclic C=C double bond in position 2 of the hetero ring have a wide spectrum of biological activity, but their fungicidal activity has not been studied as much as it should be. This paper presents a simple and convenient approach for obtaining potential antifungal agents based on 2-(4-oxo-1,3-thiazolidin-2-ylidene)acetamides. The first examples of evaluating the fungicidal activity of 8 obtained compounds on 8 strains of phytopathogenic fungi are presented. A highly active compound 4e with EC50 of 0.85 and 2.29 µg/mL against A. solani and P. lingam, respectively, was found to be promising for further study.

UR - http://www.scopus.com/inward/record.url?partnerID=8YFLogxK&scp=85147422194

UR - https://elibrary.ru/item.asp?id=50757179

U2 - 10.15826/chimtech.2023.10.1.06

DO - 10.15826/chimtech.2023.10.1.06

M3 - Article

VL - 10

JO - Chimica Techno Acta

JF - Chimica Techno Acta

SN - 2409-5613

IS - 1

ER -

ID: 34722551