TY - JOUR

T1 - Unsolved morphogenesis problems and the hidden order

AU - Melkikh, A. V.

PY - 2024

Y1 - 2024

N2 - In this work, the morphogenesis mechanisms are considered from the complexity perspective. It is shown that both morphogenesis and the functioning of organs should be unstable in the case of short-range interaction potentials. The repeatability of forms during evolution is a strong argument for its directionality. The formation of organs during evolution can occur only in the presence of a priori information about the structure of such an organ. The focus of the discussion is not merely on constraining potential possibilities but on the concept of directed evolution itself. A morphogenesis model was constructed based on nontrivial quantum effects. These interaction effects between biologically important molecules ensure the accurate synthesis of cells, tissues, and organs.

AB - In this work, the morphogenesis mechanisms are considered from the complexity perspective. It is shown that both morphogenesis and the functioning of organs should be unstable in the case of short-range interaction potentials. The repeatability of forms during evolution is a strong argument for its directionality. The formation of organs during evolution can occur only in the presence of a priori information about the structure of such an organ. The focus of the discussion is not merely on constraining potential possibilities but on the concept of directed evolution itself. A morphogenesis model was constructed based on nontrivial quantum effects. These interaction effects between biologically important molecules ensure the accurate synthesis of cells, tissues, and organs.

UR - http://www.scopus.com/inward/record.url?partnerID=8YFLogxK&scp=85191015370

U2 - 10.1016/j.biosystems.2024.105218

DO - 10.1016/j.biosystems.2024.105218

M3 - Book/Film/Article review

VL - 239

JO - BioSystems

JF - BioSystems

SN - 0303-2647

M1 - 105218

ER -