Standard

The Development of Tablets containing Vinpocetine and Ginkgo biloba L. Extract. / Slovesnova, N.; Petrov, A; Glavatskih, S. et al.
In: International Journal of Drug Delivery Technology, Vol. 13, No. 04, 2023, p. 1139-1144.

Research output: Contribution to journal › Article › peer-review

Harvard

Slovesnova, N, Petrov, A, Glavatskih, S, Bolotova, АV & Kopchuk, D 2023, 'The Development of Tablets containing Vinpocetine and Ginkgo biloba L. Extract', International Journal of Drug Delivery Technology, vol. 13, no. 04, pp. 1139-1144. https://doi.org/10.25258/ijddt.13.4.02

APA

Slovesnova, N., Petrov, A., Glavatskih, S., Bolotova, А. V., & Kopchuk, D. (2023). The Development of Tablets containing Vinpocetine and Ginkgo biloba L. Extract. International Journal of Drug Delivery Technology, 13(04), 1139-1144. https://doi.org/10.25258/ijddt.13.4.02

Vancouver

Slovesnova N, Petrov A, Glavatskih S, Bolotova АV, Kopchuk D. The Development of Tablets containing Vinpocetine and Ginkgo biloba L. Extract. International Journal of Drug Delivery Technology. 2023;13(04):1139-1144. doi: 10.25258/ijddt.13.4.02

Author

Slovesnova, N. ; Petrov, A ; Glavatskih, S. et al. / The Development of Tablets containing Vinpocetine and Ginkgo biloba L. Extract. In: International Journal of Drug Delivery Technology. 2023 ; Vol. 13, No. 04. pp. 1139-1144.

BibTeX

@article{947e275c10c54816825d92b806681f93,
title = "The Development of Tablets containing Vinpocetine and Ginkgo biloba L. Extract",
abstract = "The release rate of active pharmaceutical ingredients (APIs) from tablet dosage forms is significantly influenced by the composition of the formulation, in particular filler composition. In this work, we analyzed the impact of the ratio of excipients on the release rate of vinpocetine from a tablet containing Ginkgo biloba L. extract as the second API. Microcrystalline cellulose (MCC), hydroxypropylcellulose (L-HPC) mixed with MCC (up to 16% of HPC), and partially pregelatinized starch were used in different ratios as excipients. Moreover, tween-80 was used to study the effect of introduction of emulsifier on the APIs{\textquoteright} release rates. According to our findings, optimal APIs{\textquoteright} release rates are achieved when using the combination of MCC with HPC at a ratio of 2:3.",
author = "N. Slovesnova and A Petrov and S. Glavatskih and Bolotova, {А. V.} and D. Kopchuk",
year = "2023",
doi = "10.25258/ijddt.13.4.02",
language = "English",
volume = "13",
pages = "1139--1144",
journal = "International Journal of Drug Delivery Technology",
issn = "0975-4415",
publisher = "Dr. Yashwant Research Labs Pvt. Ltd.",
number = "04",

}

RIS

TY - JOUR

T1 - The Development of Tablets containing Vinpocetine and Ginkgo biloba L. Extract

AU - Slovesnova, N.

AU - Petrov, A

AU - Glavatskih, S.

AU - Bolotova, А. V.

AU - Kopchuk, D.

PY - 2023

Y1 - 2023

N2 - The release rate of active pharmaceutical ingredients (APIs) from tablet dosage forms is significantly influenced by the composition of the formulation, in particular filler composition. In this work, we analyzed the impact of the ratio of excipients on the release rate of vinpocetine from a tablet containing Ginkgo biloba L. extract as the second API. Microcrystalline cellulose (MCC), hydroxypropylcellulose (L-HPC) mixed with MCC (up to 16% of HPC), and partially pregelatinized starch were used in different ratios as excipients. Moreover, tween-80 was used to study the effect of introduction of emulsifier on the APIs’ release rates. According to our findings, optimal APIs’ release rates are achieved when using the combination of MCC with HPC at a ratio of 2:3.

AB - The release rate of active pharmaceutical ingredients (APIs) from tablet dosage forms is significantly influenced by the composition of the formulation, in particular filler composition. In this work, we analyzed the impact of the ratio of excipients on the release rate of vinpocetine from a tablet containing Ginkgo biloba L. extract as the second API. Microcrystalline cellulose (MCC), hydroxypropylcellulose (L-HPC) mixed with MCC (up to 16% of HPC), and partially pregelatinized starch were used in different ratios as excipients. Moreover, tween-80 was used to study the effect of introduction of emulsifier on the APIs’ release rates. According to our findings, optimal APIs’ release rates are achieved when using the combination of MCC with HPC at a ratio of 2:3.

UR - http://www.scopus.com/inward/record.url?partnerID=8YFLogxK&scp=85185682800

U2 - 10.25258/ijddt.13.4.02

DO - 10.25258/ijddt.13.4.02

M3 - Article

VL - 13

SP - 1139

EP - 1144

JO - International Journal of Drug Delivery Technology

JF - International Journal of Drug Delivery Technology

SN - 0975-4415

IS - 04

ER -

ID: 53807061