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Synthesis of Novel Memantine and Rimantadine Derivatives as Promising Drug Candidates. / Shtaitz, Ya.; Ladin, E.; Slovesnova, N. et al.
In: Russian Journal of General Chemistry, Vol. 93, No. S1, 2023, p. S100-S105.

Research output: Contribution to journal › Article › peer-review

Harvard

Shtaitz, Y, Ladin, E, Slovesnova, N, Krasnoperova, K, Kopchuk, D, Zyryanov, G & Rusinov, V 2023, 'Synthesis of Novel Memantine and Rimantadine Derivatives as Promising Drug Candidates', Russian Journal of General Chemistry, vol. 93, no. S1, pp. S100-S105. https://doi.org/10.1134/S1070363223140244

APA

Shtaitz, Y., Ladin, E., Slovesnova, N., Krasnoperova, K., Kopchuk, D., Zyryanov, G., & Rusinov, V. (2023). Synthesis of Novel Memantine and Rimantadine Derivatives as Promising Drug Candidates. Russian Journal of General Chemistry, 93(S1), S100-S105. https://doi.org/10.1134/S1070363223140244

Vancouver

Shtaitz Y, Ladin E, Slovesnova N, Krasnoperova K, Kopchuk D, Zyryanov G et al. Synthesis of Novel Memantine and Rimantadine Derivatives as Promising Drug Candidates. Russian Journal of General Chemistry. 2023;93(S1):S100-S105. doi: 10.1134/S1070363223140244

Author

Shtaitz, Ya. ; Ladin, E. ; Slovesnova, N. et al. / Synthesis of Novel Memantine and Rimantadine Derivatives as Promising Drug Candidates. In: Russian Journal of General Chemistry. 2023 ; Vol. 93, No. S1. pp. S100-S105.

BibTeX

@article{852ff2d82e744282986c3323a3beb92c,
title = "Synthesis of Novel Memantine and Rimantadine Derivatives as Promising Drug Candidates",
abstract = "A convenient method has been proposed for the preparation of new derivatives of adamantine-based drugs, such as memantine and rimantadine. The synthesis was performed by functionalization of amino-group of memantine and rimantadine by ipso-substitution of cyano-group at C5 position of 1,2,4-triazine scaffold with the corresponding aminoadamantane moieties with subsequent aza-Diels–Alder transformation of 1,2,4-triazine cycle into pyridine one in some cases. {\textcopyright} 2023, Pleiades Publishing, Ltd.",
author = "Ya. Shtaitz and E. Ladin and N. Slovesnova and K. Krasnoperova and D. Kopchuk and G. Zyryanov and V. Rusinov",
note = "This work was supported by the Russian Science Foundation (grant no. 23-73-10158, https://rscf.ru/project/23-73-10158/).",
year = "2023",
doi = "10.1134/S1070363223140244",
language = "English",
volume = "93",
pages = "S100--S105",
journal = "Russian Journal of General Chemistry",
issn = "1070-3632",
publisher = "Maik Nauka-Interperiodica Publishing",
number = "S1",

}

RIS

TY - JOUR

T1 - Synthesis of Novel Memantine and Rimantadine Derivatives as Promising Drug Candidates

AU - Shtaitz, Ya.

AU - Ladin, E.

AU - Slovesnova, N.

AU - Krasnoperova, K.

AU - Kopchuk, D.

AU - Zyryanov, G.

AU - Rusinov, V.

N1 - This work was supported by the Russian Science Foundation (grant no. 23-73-10158, https://rscf.ru/project/23-73-10158/).

PY - 2023

Y1 - 2023

N2 - A convenient method has been proposed for the preparation of new derivatives of adamantine-based drugs, such as memantine and rimantadine. The synthesis was performed by functionalization of amino-group of memantine and rimantadine by ipso-substitution of cyano-group at C5 position of 1,2,4-triazine scaffold with the corresponding aminoadamantane moieties with subsequent aza-Diels–Alder transformation of 1,2,4-triazine cycle into pyridine one in some cases. © 2023, Pleiades Publishing, Ltd.

AB - A convenient method has been proposed for the preparation of new derivatives of adamantine-based drugs, such as memantine and rimantadine. The synthesis was performed by functionalization of amino-group of memantine and rimantadine by ipso-substitution of cyano-group at C5 position of 1,2,4-triazine scaffold with the corresponding aminoadamantane moieties with subsequent aza-Diels–Alder transformation of 1,2,4-triazine cycle into pyridine one in some cases. © 2023, Pleiades Publishing, Ltd.

UR - http://www.scopus.com/inward/record.url?partnerID=8YFLogxK&scp=85178877397

UR - https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=tsmetrics&SrcApp=tsm_test&DestApp=WOS_CPL&DestLinkType=FullRecord&KeyUT=001117621900019

U2 - 10.1134/S1070363223140244

DO - 10.1134/S1070363223140244

M3 - Article

VL - 93

SP - S100-S105

JO - Russian Journal of General Chemistry

JF - Russian Journal of General Chemistry

SN - 1070-3632

IS - S1

ER -

ID: 49827948