Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
}
TY - JOUR
T1 - Synthesis of Novel Derivatives of 5-Aryl/thienyl-[1,2,4]triazolo[4,3-c]quinazoline
AU - Nosova, E. V.
AU - Kopotilova, A. E.
AU - Likhacheva, M. D.
AU - Moshkina, T. N.
AU - Kopchuk, D. S.
N1 - The study was financially supported by the Ministry of Science and Higher Education of the Russian Federation (State contract no. FEUZ-2020-0058 (Н687/42B.223/20)).
PY - 2022/8/1
Y1 - 2022/8/1
N2 - [1,2,4]Triazolo[4,3-c]quinazolines bearing p-bromophenyl or 5-bromothiophen-2-yl moiety at position 5 have been synthesized by cyclocondensation of the corresponding 4-hydrazinoquinazolines with ortho esters in boiling ethanol or glacial acidic acid. The synthesized tricyclic derivatives represent valuable intermediates for design of fluorophores and biologically active compounds. The possibility of modifying 5-(4-bromophenyl) derivatives by cross-coupling reaction has been demonstrated.
AB - [1,2,4]Triazolo[4,3-c]quinazolines bearing p-bromophenyl or 5-bromothiophen-2-yl moiety at position 5 have been synthesized by cyclocondensation of the corresponding 4-hydrazinoquinazolines with ortho esters in boiling ethanol or glacial acidic acid. The synthesized tricyclic derivatives represent valuable intermediates for design of fluorophores and biologically active compounds. The possibility of modifying 5-(4-bromophenyl) derivatives by cross-coupling reaction has been demonstrated.
UR - http://www.scopus.com/inward/record.url?partnerID=8YFLogxK&scp=85147170840
UR - https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=tsmetrics&SrcApp=tsm_test&DestApp=WOS_CPL&DestLinkType=FullRecord&KeyUT=000925560600002
U2 - 10.1134/S0012500822600298
DO - 10.1134/S0012500822600298
M3 - Article
VL - 505
SP - 164
EP - 167
JO - Doklady Chemistry
JF - Doklady Chemistry
SN - 0012-5008
IS - 2
ER -
ID: 34713519