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Synthesis of derivatives of 6-aryl-2,2′-bipyridine complexes with PtII as potential antitumor agents. / Abramov, V.; Cheremnykh, L.; El’tsov, O. et al.
In: Russian Chemical Bulletin, Vol. 72, No. 12, 01.12.2023, p. 2848-2859.

Research output: Contribution to journal › Article › peer-review

Harvard

Abramov, V, Cheremnykh, L, El’tsov, O, Tokhtueva, M, Melekhin, V, Paramonova, A, Mezentseva, A, Chernysheva, A & Makeev, O 2023, 'Synthesis of derivatives of 6-aryl-2,2′-bipyridine complexes with PtII as potential antitumor agents', Russian Chemical Bulletin, vol. 72, no. 12, pp. 2848-2859. https://doi.org/10.1007/s11172-023-4094-5

APA

Abramov, V., Cheremnykh, L., El’tsov, O., Tokhtueva, M., Melekhin, V., Paramonova, A., Mezentseva, A., Chernysheva, A., & Makeev, O. (2023). Synthesis of derivatives of 6-aryl-2,2′-bipyridine complexes with PtII as potential antitumor agents. Russian Chemical Bulletin, 72(12), 2848-2859. https://doi.org/10.1007/s11172-023-4094-5

Vancouver

Abramov V, Cheremnykh L, El’tsov O, Tokhtueva M, Melekhin V, Paramonova A et al. Synthesis of derivatives of 6-aryl-2,2′-bipyridine complexes with PtII as potential antitumor agents. Russian Chemical Bulletin. 2023 Dec 1;72(12):2848-2859. doi: 10.1007/s11172-023-4094-5

Author

Abramov, V. ; Cheremnykh, L. ; El’tsov, O. et al. / Synthesis of derivatives of 6-aryl-2,2′-bipyridine complexes with PtII as potential antitumor agents. In: Russian Chemical Bulletin. 2023 ; Vol. 72, No. 12. pp. 2848-2859.

BibTeX

@article{e924d72ec3fb4b14a9ce1138d2e39bea,
title = "Synthesis of derivatives of 6-aryl-2,2′-bipyridine complexes with PtII as potential antitumor agents",
abstract = "New PtII complexes of aryl- and diaryl-2,2′-bipyridines were prepared using the Kr{\"o}hnke method for the further synthesis of pyridine derivatives. Signal assignment in the 1H and 13C NMR spectra was performed for the 1D and 2D NMR spectral data. The primary screening evaluation of the antitumor activity of the synthesized compounds on cultured human cells in vitro showed high biological significance of selected samples. The cell death under the action of the studied compounds proceeds via apoptosis type as shown by fluorescent dyeing and polymerase chain reaction in the real time.",
author = "V. Abramov and L. Cheremnykh and O. El{\textquoteright}tsov and M. Tokhtueva and V. Melekhin and A. Paramonova and A. Mezentseva and A. Chernysheva and O. Makeev",
note = "This work was financially supported by the Russian Science Foundation (Project No. 23-23-00375).",
year = "2023",
month = dec,
day = "1",
doi = "10.1007/s11172-023-4094-5",
language = "English",
volume = "72",
pages = "2848--2859",
journal = "Russian Chemical Bulletin",
issn = "1066-5285",
publisher = "Springer",
number = "12",

}

RIS

TY - JOUR

T1 - Synthesis of derivatives of 6-aryl-2,2′-bipyridine complexes with PtII as potential antitumor agents

AU - Abramov, V.

AU - Cheremnykh, L.

AU - El’tsov, O.

AU - Tokhtueva, M.

AU - Melekhin, V.

AU - Paramonova, A.

AU - Mezentseva, A.

AU - Chernysheva, A.

AU - Makeev, O.

N1 - This work was financially supported by the Russian Science Foundation (Project No. 23-23-00375).

PY - 2023/12/1

Y1 - 2023/12/1

N2 - New PtII complexes of aryl- and diaryl-2,2′-bipyridines were prepared using the Kröhnke method for the further synthesis of pyridine derivatives. Signal assignment in the 1H and 13C NMR spectra was performed for the 1D and 2D NMR spectral data. The primary screening evaluation of the antitumor activity of the synthesized compounds on cultured human cells in vitro showed high biological significance of selected samples. The cell death under the action of the studied compounds proceeds via apoptosis type as shown by fluorescent dyeing and polymerase chain reaction in the real time.

AB - New PtII complexes of aryl- and diaryl-2,2′-bipyridines were prepared using the Kröhnke method for the further synthesis of pyridine derivatives. Signal assignment in the 1H and 13C NMR spectra was performed for the 1D and 2D NMR spectral data. The primary screening evaluation of the antitumor activity of the synthesized compounds on cultured human cells in vitro showed high biological significance of selected samples. The cell death under the action of the studied compounds proceeds via apoptosis type as shown by fluorescent dyeing and polymerase chain reaction in the real time.

UR - http://www.scopus.com/inward/record.url?partnerID=8YFLogxK&scp=85183912766

UR - https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=tsmetrics&SrcApp=tsm_test&DestApp=WOS_CPL&DestLinkType=FullRecord&KeyUT=001154671000023

U2 - 10.1007/s11172-023-4094-5

DO - 10.1007/s11172-023-4094-5

M3 - Article

VL - 72

SP - 2848

EP - 2859

JO - Russian Chemical Bulletin

JF - Russian Chemical Bulletin

SN - 1066-5285

IS - 12

ER -

ID: 52954905