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Recent Trends in the Antidiabetic Prominence of Natural and Synthetic Analogues of Aurones. / Aluru, Rammohan; Mukherjee, Anindita; Zyryanov, Grigory et al.
In: Current Issues in Molecular Biology, Vol. 45, No. 10, 2023, p. 8461-8475.

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Aluru R, Mukherjee A, Zyryanov G, Majee A, Santra S. Recent Trends in the Antidiabetic Prominence of Natural and Synthetic Analogues of Aurones. Current Issues in Molecular Biology. 2023;45(10):8461-8475. doi: 10.3390/cimb45100533

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@article{cc3dc138e8ae4a76aa6b5e7979a06244,
title = "Recent Trends in the Antidiabetic Prominence of Natural and Synthetic Analogues of Aurones",
abstract = "Natural products are a boundless source for the development of pharmaceutical agents against a wide range of human diseases. Accordingly, naturally occurring aurones possess various biological benefits, such as anticancer, antioxidant, antimicrobial, antidiabetic, anti-inflammatory, antiviral and neuroprotective effects. In addition, various studies have revealed that aurones are potential templates for the regulation of diabetes mellitus and its associated complications. Likewise, certain aurones and their analogues have been found to be remarkable kinase inhibitors of DARK2, PPAR-γ, PTPM1, AGE, α-amylase and α-glucosidase, which represents a promising approach for the treatment of chronic metabolic disorders such as diabetes. Therefore, in our present study, we provide a detailed account of the advances in aurones as antidiabetic agents over the past decade.",
author = "Rammohan Aluru and Anindita Mukherjee and Grigory Zyryanov and Adinath Majee and Sougata Santra",
note = "This research was funded by the Ministry of Science and Higher Education of the Russian Federation (Ural Federal University Program of Development within the Priority-2030 Program).",
year = "2023",
doi = "10.3390/cimb45100533",
language = "English",
volume = "45",
pages = "8461--8475",
journal = "Current Issues in Molecular Biology",
issn = "1467-3037",
publisher = "Multidisciplinary Digital Publishing Institute (MDPI)",
number = "10",

}

RIS

TY - JOUR

T1 - Recent Trends in the Antidiabetic Prominence of Natural and Synthetic Analogues of Aurones

AU - Aluru, Rammohan

AU - Mukherjee, Anindita

AU - Zyryanov, Grigory

AU - Majee, Adinath

AU - Santra, Sougata

N1 - This research was funded by the Ministry of Science and Higher Education of the Russian Federation (Ural Federal University Program of Development within the Priority-2030 Program).

PY - 2023

Y1 - 2023

N2 - Natural products are a boundless source for the development of pharmaceutical agents against a wide range of human diseases. Accordingly, naturally occurring aurones possess various biological benefits, such as anticancer, antioxidant, antimicrobial, antidiabetic, anti-inflammatory, antiviral and neuroprotective effects. In addition, various studies have revealed that aurones are potential templates for the regulation of diabetes mellitus and its associated complications. Likewise, certain aurones and their analogues have been found to be remarkable kinase inhibitors of DARK2, PPAR-γ, PTPM1, AGE, α-amylase and α-glucosidase, which represents a promising approach for the treatment of chronic metabolic disorders such as diabetes. Therefore, in our present study, we provide a detailed account of the advances in aurones as antidiabetic agents over the past decade.

AB - Natural products are a boundless source for the development of pharmaceutical agents against a wide range of human diseases. Accordingly, naturally occurring aurones possess various biological benefits, such as anticancer, antioxidant, antimicrobial, antidiabetic, anti-inflammatory, antiviral and neuroprotective effects. In addition, various studies have revealed that aurones are potential templates for the regulation of diabetes mellitus and its associated complications. Likewise, certain aurones and their analogues have been found to be remarkable kinase inhibitors of DARK2, PPAR-γ, PTPM1, AGE, α-amylase and α-glucosidase, which represents a promising approach for the treatment of chronic metabolic disorders such as diabetes. Therefore, in our present study, we provide a detailed account of the advances in aurones as antidiabetic agents over the past decade.

UR - http://www.scopus.com/inward/record.url?partnerID=8YFLogxK&scp=85175087801

UR - https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=tsmetrics&SrcApp=tsm_test&DestApp=WOS_CPL&DestLinkType=FullRecord&KeyUT=001098241800001

U2 - 10.3390/cimb45100533

DO - 10.3390/cimb45100533

M3 - Article

VL - 45

SP - 8461

EP - 8475

JO - Current Issues in Molecular Biology

JF - Current Issues in Molecular Biology

SN - 1467-3037

IS - 10

ER -

ID: 47647488