Standard

Modeling of Local Hematocrit for Blood Flow in Stenotic Coronary Vessels. / Starodumov, Ilya; Makhaeva, Ksenia; Zubarev, Andrey et al.
In: Fluids, Vol. 8, No. 8, 230, 2023.

Research output: Contribution to journal › Article › peer-review

Harvard

Starodumov, I, Makhaeva, K, Zubarev, A, Bessonov, I, Sokolov, S, Mikushin, P, Alexandrov, D, Chestukhin, V & Blyakhman, F 2023, 'Modeling of Local Hematocrit for Blood Flow in Stenotic Coronary Vessels', Fluids, vol. 8, no. 8, 230. https://doi.org/10.3390/fluids8080230

APA

Starodumov, I., Makhaeva, K., Zubarev, A., Bessonov, I., Sokolov, S., Mikushin, P., Alexandrov, D., Chestukhin, V., & Blyakhman, F. (2023). Modeling of Local Hematocrit for Blood Flow in Stenotic Coronary Vessels. Fluids, 8(8), [230]. https://doi.org/10.3390/fluids8080230

Vancouver

Starodumov I, Makhaeva K, Zubarev A, Bessonov I, Sokolov S, Mikushin P et al. Modeling of Local Hematocrit for Blood Flow in Stenotic Coronary Vessels. Fluids. 2023;8(8):230. doi: 10.3390/fluids8080230

Author

Starodumov, Ilya ; Makhaeva, Ksenia ; Zubarev, Andrey et al. / Modeling of Local Hematocrit for Blood Flow in Stenotic Coronary Vessels. In: Fluids. 2023 ; Vol. 8, No. 8.

BibTeX

@article{ebcbe65757cb43d8bc6b5b2e3c2d8f9e,
title = "Modeling of Local Hematocrit for Blood Flow in Stenotic Coronary Vessels",
abstract = "This mainly theoretical work is devoted to the study of the contribution of the cell-free layer (CFL) near the vessel wall to hemodynamics in a large coronary artery with stenosis to assess the relevance of CFL modeling to the needs of interventional cardiology. An Euler–Euler model considering blood as a two-component fluid with a discrete phase of erythrocytes and a liquid plasma phase was applied to a simple 2d vessel with 65% stenosis. It was found that both the CFL thickness and the local contribution of the CFL thickness to hemodynamics are inhomogeneous along the vessel. The effects of CFL on the velocity profiles, vortex formation, hematocrit, viscosity, and wall shear stresses in the area of stenosis were determined. To demonstrate the significance of CFL modeling for prognostic purposes, the same hemodynamic conditions, analyzed using a one-component model, were also considered. A comparison analysis showed that the existence of CFL resulted in a significant overestimation (up to over 100%) of the main hemodynamic characteristics of the flow obtained using the model based on the Carreau equation.",
author = "Ilya Starodumov and Ksenia Makhaeva and Andrey Zubarev and Ivan Bessonov and Sergey Sokolov and Pavel Mikushin and Dmitri Alexandrov and Vasiliy Chestukhin and Felix Blyakhman",
note = "This study was supported by the Russian Science Foundation (project no. 22-71-10071).",
year = "2023",
doi = "10.3390/fluids8080230",
language = "English",
volume = "8",
journal = "Fluids",
issn = "2311-5521",
publisher = "Multidisciplinary Digital Publishing Institute (MDPI)",
number = "8",

}

RIS

TY - JOUR

T1 - Modeling of Local Hematocrit for Blood Flow in Stenotic Coronary Vessels

AU - Starodumov, Ilya

AU - Makhaeva, Ksenia

AU - Zubarev, Andrey

AU - Bessonov, Ivan

AU - Sokolov, Sergey

AU - Mikushin, Pavel

AU - Alexandrov, Dmitri

AU - Chestukhin, Vasiliy

AU - Blyakhman, Felix

N1 - This study was supported by the Russian Science Foundation (project no. 22-71-10071).

PY - 2023

Y1 - 2023

N2 - This mainly theoretical work is devoted to the study of the contribution of the cell-free layer (CFL) near the vessel wall to hemodynamics in a large coronary artery with stenosis to assess the relevance of CFL modeling to the needs of interventional cardiology. An Euler–Euler model considering blood as a two-component fluid with a discrete phase of erythrocytes and a liquid plasma phase was applied to a simple 2d vessel with 65% stenosis. It was found that both the CFL thickness and the local contribution of the CFL thickness to hemodynamics are inhomogeneous along the vessel. The effects of CFL on the velocity profiles, vortex formation, hematocrit, viscosity, and wall shear stresses in the area of stenosis were determined. To demonstrate the significance of CFL modeling for prognostic purposes, the same hemodynamic conditions, analyzed using a one-component model, were also considered. A comparison analysis showed that the existence of CFL resulted in a significant overestimation (up to over 100%) of the main hemodynamic characteristics of the flow obtained using the model based on the Carreau equation.

AB - This mainly theoretical work is devoted to the study of the contribution of the cell-free layer (CFL) near the vessel wall to hemodynamics in a large coronary artery with stenosis to assess the relevance of CFL modeling to the needs of interventional cardiology. An Euler–Euler model considering blood as a two-component fluid with a discrete phase of erythrocytes and a liquid plasma phase was applied to a simple 2d vessel with 65% stenosis. It was found that both the CFL thickness and the local contribution of the CFL thickness to hemodynamics are inhomogeneous along the vessel. The effects of CFL on the velocity profiles, vortex formation, hematocrit, viscosity, and wall shear stresses in the area of stenosis were determined. To demonstrate the significance of CFL modeling for prognostic purposes, the same hemodynamic conditions, analyzed using a one-component model, were also considered. A comparison analysis showed that the existence of CFL resulted in a significant overestimation (up to over 100%) of the main hemodynamic characteristics of the flow obtained using the model based on the Carreau equation.

UR - http://www.scopus.com/inward/record.url?partnerID=8YFLogxK&scp=85169052242

UR - https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=tsmetrics&SrcApp=tsm_test&DestApp=WOS_CPL&DestLinkType=FullRecord&KeyUT=001057357300001

U2 - 10.3390/fluids8080230

DO - 10.3390/fluids8080230

M3 - Article

VL - 8

JO - Fluids

JF - Fluids

SN - 2311-5521

IS - 8

M1 - 230

ER -

ID: 44657908