Electrochemical creatinine determination with metal-organic framework catalyst based on copper and acetylenedicarboxylic acid

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Electrochemical creatinine determination with metal-organic framework catalyst based on copper and acetylenedicarboxylic acid. / Okhokhonin, Andrei v.; Izmozherova, Yulia v.; Ibatullina , Alsu A. et al.
In: Chimica Techno Acta, Vol. 10, No. 2, 202310201, 2023.

Research output: Contribution to journal › Article › peer-review

BibTeX

@article{9546b6f940b34e5cb6e0d15c7c5b4f77,

title = "Electrochemical creatinine determination with metal-organic framework catalyst based on copper and acetylenedicarboxylic acid",

abstract = "Fast and accurate determination of creatinine is critical in kidney function diagnostics. This paper discusses the usage of the metal-organic framework based on copper(II) and acetylenedicarboxylic acid (CuADCA) as a catalyst of electrochemical oxidation of creatinine, glucose and urea. CuADCA was synthesized by deprotonation with triethylamine for the first time. Successful synthesis was confirmed by FTIR and EDS. The material was characterized by SEM, EIS, and CV. CuADCA forms laminated-like flakes with diameter from 1 µm to 20 µm, which is consistent with the polymer-like structure. CV and EIS analyses showed that CuADCA immobilized on GCE acts as a catalyst in electrooxidation reaction of glucose, urea, and creatinine. The sensitivity of creatinine detection, 1057±99 µA/mM, was higher than the detection sensitivity of glucose and urea by more than 100 times with the limit of detection of 2 µM, so CuADCA is a promising material for further development of enzymeless sensors for creatinine. {\textcopyright} 2023, the Authors.",

author = "Okhokhonin, {Andrei v.} and Izmozherova, {Yulia v.} and Ibatullina, {Alsu A.} and Stepanova, {Marina I.} and Matern, {Anatoliy I.} and Kozitsina, {Alisa N.}",

note = "The research funding from the Ministry of Science and Higher Education of the Russian Federation (Ural Federal University project within the Priority-2030 Program) is gratefully acknowledged.",

year = "2023",

doi = "10.15826/chimtech.2023.10.2.01",

language = "English",

volume = "10",

journal = "Chimica Techno Acta",

issn = "2409-5613",

publisher = "Издательство Уральского университета",

number = "2",

}

RIS

TY - JOUR

T1 - Electrochemical creatinine determination with metal-organic framework catalyst based on copper and acetylenedicarboxylic acid

AU - Okhokhonin, Andrei v.

AU - Izmozherova, Yulia v.

AU - Ibatullina , Alsu A.

AU - Stepanova, Marina I.

AU - Matern, Anatoliy I.

AU - Kozitsina, Alisa N.

N1 - The research funding from the Ministry of Science and Higher Education of the Russian Federation (Ural Federal University project within the Priority-2030 Program) is gratefully acknowledged.

PY - 2023

Y1 - 2023

N2 - Fast and accurate determination of creatinine is critical in kidney function diagnostics. This paper discusses the usage of the metal-organic framework based on copper(II) and acetylenedicarboxylic acid (CuADCA) as a catalyst of electrochemical oxidation of creatinine, glucose and urea. CuADCA was synthesized by deprotonation with triethylamine for the first time. Successful synthesis was confirmed by FTIR and EDS. The material was characterized by SEM, EIS, and CV. CuADCA forms laminated-like flakes with diameter from 1 µm to 20 µm, which is consistent with the polymer-like structure. CV and EIS analyses showed that CuADCA immobilized on GCE acts as a catalyst in electrooxidation reaction of glucose, urea, and creatinine. The sensitivity of creatinine detection, 1057±99 µA/mM, was higher than the detection sensitivity of glucose and urea by more than 100 times with the limit of detection of 2 µM, so CuADCA is a promising material for further development of enzymeless sensors for creatinine. © 2023, the Authors.

AB - Fast and accurate determination of creatinine is critical in kidney function diagnostics. This paper discusses the usage of the metal-organic framework based on copper(II) and acetylenedicarboxylic acid (CuADCA) as a catalyst of electrochemical oxidation of creatinine, glucose and urea. CuADCA was synthesized by deprotonation with triethylamine for the first time. Successful synthesis was confirmed by FTIR and EDS. The material was characterized by SEM, EIS, and CV. CuADCA forms laminated-like flakes with diameter from 1 µm to 20 µm, which is consistent with the polymer-like structure. CV and EIS analyses showed that CuADCA immobilized on GCE acts as a catalyst in electrooxidation reaction of glucose, urea, and creatinine. The sensitivity of creatinine detection, 1057±99 µA/mM, was higher than the detection sensitivity of glucose and urea by more than 100 times with the limit of detection of 2 µM, so CuADCA is a promising material for further development of enzymeless sensors for creatinine. © 2023, the Authors.

UR - http://www.scopus.com/inward/record.url?partnerID=8YFLogxK&scp=85158850682

UR - https://elibrary.ru/item.asp?id=54268143

U2 - 10.15826/chimtech.2023.10.2.01

DO - 10.15826/chimtech.2023.10.2.01

M3 - Article

VL - 10

JO - Chimica Techno Acta

JF - Chimica Techno Acta

SN - 2409-5613

IS - 2

M1 - 202310201

ER -

ID: 39242040