To date, a key area of research in the field of nanostructured materials science and methods of obtaining nanostructures is the study of the effect of physicochemical and structural properties on their conductive characteristics. In contrast to macroobjects for nanostructures, factors such as the size of grains and the concentration of their boundaries, dislocation and defect densities, the degree of ordering of the structure, etc. have a tremendous effect on the conducting properties, as well as the magnitude of the resistance. In this case, in most cases, nanosize can lead to extraordinary changes in the conductivity of nanostructures. The purpose of this chapter is to present the results of the influence of various conditions for the synthesis of copper nanostructures, as well as various methods of modification using ionizing radiation on their conducting properties.