The distribution maps of natural radioelement (40K, 232Th and 238U) over the Wadi El Bohlog–Wadi Kam Amiri region of Egypt desert were shown. Granitic rocks, characteristic building materials of the study region, were analyzed: (1) the radionuclides contents were determined by using NaI detector; (2) minerals were investigated by an environmental scan electron microscope (ESEM). The average values of 238U, 232Th, 40K are higher than the worldwide average. This is due to the main mineral composition of the granitic rock samples, like thorite, uranothorite, kasolite, zircon and xenotime. Radiological hazards indexes were computed to evaluate the radioactive risk of these rocks to the public, showing high values exceeding the worldwide limits.