In this study, theories of aging and its mechanisms under various environmental conditions were analyzed. The analysis of published data suggested that aging is a controlled process. It is known that many mathematical algorithms utilize an analogy of aging. However, this is possible only when a “target set” is known in advance. Various forms of selection in relation to aging were analyzed both collectively and separately. The general conclusion is that aging is one of the mechanisms of directed evolution. A model was constructed, which shows how aging is integrated into partially directed evolution.