The purpose of the article is to analyze the Taiwan issue as a key one for the foreign policy of China and the United States at the present time. Since the Second World War, relations between mainland China and Taiwan have been tense, and the United States has played an important role in aggravating the Taiwan issue. The authors consider the development of Sino-American relations in Northeast Asia at the beginning of the XXI century, their impact on the Taiwan issue. Such issues as the modernization of Taiwan’s industry, the strategy of Taiwan’s liberation by China, the problem of Taiwan’s “independence”, the unrest in Hong Kong, the crisis in the Taiwan Strait associated with Pelosi’s visit to Taiwan are analyzed. The similarity of the Taiwan crisis and the Special Military Operation in Ukraine is shown. It is concluded that the solution of the Taiwan issue is in a stage of uncertainty, and this uncertainty is caused by US interference in China’s internal affairs. The Taiwan issue must be resolved peacefully, this requires not only the joint efforts of the Chinese government and Taiwan, but also the cessation of US interference in the Taiwan issue.