The ongoing transition of the world thermal power industry to ultra-supercritical steam parameters makes it possible to significantly increase efficiency and reduce fuel consumption, as well as reduce the discharge of harmful substances into the environment. To maintain competitiveness in the NPP electricity market, it is necessary to increase its efficiency. One of the possible ways to improve the energy efficiency of nuclear power plants with fast reactors is to improve the thermodynamic cycle. The paper presents the results of computer simulation of options for cycle arrangements of NPPs with the BREST-OD-300 reactor using non-nuclear steam superheating, as well as steam compression to increase the thermodynamic efficiency of the cycle of the K-300-240 turbine unit and an assessment of the efficiency of using these cycle arrangements.