This article provides Russian and foreign experience of successful implementation of projects for redevelopment of industrial zones in large cities. Some projects implemented in Moscow, St. Petersburg are considered in more details. Among foreign projects, the experience of such countries as Great Britain, the USA and China (Hong Kong) should be especially noted. The redevelopment of the industrial zones of large cities in Russia is necessary for the implementation of integrated development and improvement of the territories of the central part of the cities, where industrial enterprises and factories were previously located. Industrial zones occupy many hectares of land, making cities uncomfortable for people living and resting. The implementation of redevelopment projects in the Russian Federation started in 2004. Having studied the history of the issue and foreign experience, the authors of the article highlight the existing problems facing the redevelopment of territories and offer some ways to solve this problem. At present, part of the industrial zones in Moscow and St. Petersburg has been almost completely reorganized. Instead of such zones there are residential complexes, social and cultural facilities, shopping and entertainment centers, roads, parking lots now. Modern economy requires redevelopment, because sometime it is necessary to save and update existing enterprises. The authors of the article see a way out of this situation in the creation of a clear concept in Russia for the transformation and redevelopment of industrial zones. And each specific object should become part of the system plan for the strategic development of the city and be supported by the municipality.