The electronic medical equipment developing process includes the problems and tasks of medical devices’ technical characteristics improvement, using alternative physical methods of recording medical information. Medical electronic equipment includes defibrillation equipment of various classes, the modernization of which is inextricably connected with scientific and technical research in the field of physics, circuit engineering, design, technology, modeling, characteristics’ measurement, as well as medicine. One of the interdisciplinary research areas at the cardiology and engineering issue is the development of new and modernisation of existing defibrillation devices, improving their functional and operational characteristics, as well as their application efficiency, which is necessary for the provision of extended resuscitation measures. This research is devoted to the research and modeling of defibrillator performance characteristics taking into account components reliability and the operational failure rate determination. The paper also contains study of the production process optimizing methods, in particular assembly operations of high-tech defibrillation products, where the search of optimization solutions was carried out using simulation modeling.